Its targeted mechanism of action makes it a valuable compound for investigating how NNMT inhibition influences metabolic health, mitochondrial function, and longevity-associated biological processes
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For glucose-stimulated gut hormone secretion in mice, glucose (2 g/kg body weight) was administered by oral gavage, and blood samples were collected via cheek bleeds 15 minutes later to determine plasma concentrations of gut hormones and insulin and blood glucose levels
